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. 2012 May 18;7(5):e37244. doi: 10.1371/journal.pone.0037244

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De Burghgraeve et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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P388D1 cells were infected with DENV pre-opsonized with anti-E mAb DV2-104 at an MOI of 10 in presence of increasing concentrations of LCTA-949. Anti-E DV2-104 was used at a concentration of 400 ng/ml. The percentage of inhibition of infection after LCTA-949 treatment was calculated with respect to the positive control of untreated opsonized virus. Data are expressed as the means ± SD from two separate experiments, each of which was carried out in duplicate.