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. 2012 May 18;7(5):e37311. doi: 10.1371/journal.pone.0037311

Figure 2. Loss of IL-23 in the context of functional IL-12 results in increased epithelial cell death and loss of goblet cells.

Figure 2

(A) 20X magnification of TUNEL-positive (brown) or (C) Alcian Blue (blue) cells of representative infected cecal sections. The bar in (A) and (C) represents 20 micron. The mean ± SE of TUNEL (B) positive cells per high-power field was quantified from cecal sections WT (n = 4), p19−/− (n = 5), p35−/− (n = 6) and p40−/− (n = 3) mice. The mean ± SE Alcian Blue positive cells were quantified per high-power field from cecal sections of the same mice (n = 3 per group). Statistical significance for (B and D) was determined using the one way ANOVA followed by Bonferroni post test. *: p<0.05, **: p<0.01, ***: p<0.001.