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. 2012 May 18;7(5):e37311. doi: 10.1371/journal.pone.0037311

Figure 6. IL-23 inhibits Salmonella induced IFN-γ production by lamina propria NK cells.

Figure 6

(A) LP populations isolated from WT, p19−/−, p35−/−, p40−/− and IFN-γ−/− mice were stained for surface expression of NK1.1 and CD3ε; numbers indicate the percentage of cells in the gated box. (B) Intracellular production of IFN-γ and TNF is shown for NK cells (the NK1.1+CD3 population gated in A). (C) The percentage of LP IFN-γ+ NK cells were quantified for the aforementioned mice at 3 d Salmonella infection. Plotted are the mean ± SE for 3 mice per condition. Statistical significance was determined using the one-way ANOVA followed by Bonferroni post test. *: p<0.05, **: p<0.01, ***: p<0.001