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. 2012 May 18;7(5):e37322. doi: 10.1371/journal.pone.0037322

Figure 1. Strain-dependent differences in tumor blood flow during PDT.

Figure 1

(A) Representative rBF time-courses in RIF tumors for a C3H and a nude mouse during 30 minutes of illumination with PDT (t = 0). The lines A and B represent the change points marking the beginning of the decrease in rBF and the plateau in rBF level, respectively, and were used to define the change in rBF (i.e. ΔBF = rBFA−rBFB). (B) Box plots of blood flow changes (ΔBF) during PDT within animals of each strain (N = 7 for each strain); PDT decreased rBF in both groups (p = 0.016 for both C3H and nudes), with the decrease in C3H larger than that in nudes (p = 0.026).