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. 2012 May 18;7(5):e35369. doi: 10.1371/journal.pone.0035369

Figure 11. Apoptosis cascade representing the present and absent proteins in the pyrosequencing results.

Figure 11

Proteins appearing in the turbot transcriptome are represented in reddish color and absent proteins in grey color. Fas-L: Fas ligand; TRAIL: TNF-related apoptosis-inducing ligand; TNFα: Tumor necrosis factor alpha; IL-1: interleukin 1; NGF: nerve growth factor; IL-3: interleukin 3; Fas: tumor necrosis factor receptor superfamily member 6; FAIM2: Fas apoptotic inhibitory molecule 2; TRAIL-R: tumor necrosis factor receptor superfamily member 10; TRAIL-R Decoy: TRAIL receptor with a truncated death domain; TNF-R1: tumor necrosis factor receptor superfamily member 1A; IL-1R: interleukin 1 receptor; TrkA: neurotrophic tyrosine kinase receptor type 1; IL-3R: interleukin 3 receptor; FADD: FAS-associated via death domain; TRADD: TNF receptor superfamily 1alpha-associated via death domain; MyD88: myeloid differentiation primary response protein MyD88; PTEN: Phosphatase and tensin homolog; PI3K: phosphatidylinositol-4,5-bisphosphate 3-kinase; RIP1: receptor-interacting serine/threonine-protein kinase 1; IRAK: interleukin-1 receptor-associated kinase; TRAF2: TNF receptor-associated factor 2; AKT: TNF receptor-associated factor; PKB: protein kinase B; PKA: protein kinase A; NIK: NF-kappa-beta-inducing kinase; FLIP: FADD-like apoptosis regulator; BCL-2: B cell lymphoma 2; IKK: inhibitor of nuclear factor kappa-B kinase; Bad: BCL2-antagonist of cell death; CASP3: caspase 3; CASP6: caspase 6; CASP7: caspase 7; CASP8: caspase 8; CASP9: caspase 9; CASP10: caspase 10; CASP12: caspase 12; Bid: BH3 interacting domain death agonist; CyC: cytochrome c; Apaf-1: apoptotic protease-activating factor; IAP: inhibitor of apoptosis protein; SMAC: second mitochondria-derived activator of caspases; IκBα: NF-kappa-B inhibitor alpha; NF-κB: nuclear factor NF-kappa-B; DFF45: DNA fragmentation factor of 45 kD; DFF40: DNA fragmentation factor of 40 kD; BI-1: Bax inhibitor-1; AIF: apoptosis-inducing factor; ENDO-G: endonuclease G; Bcl-XL: B-cell lymphoma-extra large; Bax: Bcl-2-associated X protein; p53: tumor protein p53; ATM: ataxia telangectasia mutated family protein.