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. 2012 May 18;7(5):e36590. doi: 10.1371/journal.pone.0036590

Figure 1. Pedigree of a 5-generational Chinese Han family affected with CADASIL.

Figure 1

Squares and circles indicate males and females, respectively. Filled symbols denote affected status. Normal individuals are shown as empty symbols. Mutation carriers without evident clinical features are indicated by a circle with a vertical line in the middle (III:31, III:33, III:34, IV:30) or a square with a vertical line in the middle (IV:28). II:4 had a large area cerebral infarction but was not a CADASIL patient.