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. 2012 May 18;7(5):e37207. doi: 10.1371/journal.pone.0037207

Figure 1. Effect of MRLB-11055 on JAK2-dependent cell lines grown in vitro.

Figure 1

A. Structure of MRLB-11055. B. Effect on proliferation of BaF3 JAK2 V617F cells over 48 hours. C. Effect on phosphoSTAT5 levels in JAK2-expressing BaF3 cells. D. Effect of 75 nM MRLB-11055 on level of apoptosis in BaF3 JAK2 cells over 48 hours.