Table 3. Distribution of 35 virulence genes among the isolates of MuH MRSA from Shanghai and Wenzhou, China.
| Gene | No. of isolates positive for the gene [% of total (n = 53)] | No.of isolates positive for the gene in two regions (%) | χ2 (P value) | ||
| Shanghai (n = 28) | Wenzhou (n = 25) | ||||
| Involved in toxin mediated disease and/or sepsis | |||||
| sea | 29 (54.7) | 9 (32.1) | 20 (80.0) | 12.208 (<0.001) | |
| seb | 0 | 0 | 0 | NA | |
| sec | 12 (22.6) | 12 (42.9) | 0 | 13.850 (<0.001) | |
| sed | 0 | 0 | 0 | NA | |
| see | 0 | 0 | 0 | NA | |
| seg | 20(37.7) | 16 (57.1) | 4 (16.0) | 9.515 (0.002) | |
| seh | 0 | 0 | 0 | NA | |
| sei | 15 (28.3) | 15 (53.6) | 0 | 18.680 (<0.001) | |
| sej | 2 (3.8) | 2 (7.1) | 0 | (0.492)* | |
| tst | 14 (26.4) | 14 (50.0) | 0 | 16.987 (<0.001) | |
| eta | 0 | 0 | 0 | NA | |
| etb | 0 | 0 | 0 | NA | |
| hla | 52 (98.1) | 27 (96.4) | 25 (100) | (1.000)* | |
| hlb | 43 (81.1) | 21 (75.0) | 22 (88.0) | 0.733 (0.392) | |
| hld | 0 | 0 | 0 | NA | |
| Involved in attachment | |||||
| fnbA | 48 (90.6) | 26 (92.9) | 22 (88.0) | 0.018 (0.894) | |
| fnbB | 8 (15.1) | 7 (25.0) | 1 (4.0) | 3.045 (0.081) | |
| clfA | 41 (77.4) | 21 (75.0) | 20 (80.0) | 0.189 (0.664) | |
| clfB | 52 (98.1) | 27 (96.4) | 25 (100) | (1.000)* | |
| cna | 42 (79.2) | 19 (67.9) | 23 (92.0) | 4.681 (0.031) | |
| bbp | 7 (13.2) | 6 (21.4) | 1 (4.0) | 2.145 (0.143) | |
| ebpS | 50 (94.3) | 27 (96.4) | 23 (92.0) | 0.010 (0.919) | |
| Involved in evading/destroying host defenses | |||||
| pvl | 8 (15.1) | 8 (28.6) | 0 | 6.331 (0.012) | |
| hlg | 46 (86.8) | 22 (78.6) | 24 (96.0) | 2.145 (0.143) | |
| hlgv | 7 (13.2) | 6 (21.4) | 1 (4.0) | 2.145 (0.143) | |
| cap-5 | 0 | 0 | 0 | NA | |
| cap-8 | 48 (90.6) | 23 (82.1) | 25 (100) | 3.061 (0.080) | |
| map | 44 (83.0) | 23 (82.1) | 21 (84.0) | 0.000 (1.000) | |
| sbi | 51 (96.2) | 28 (100) | 23 (92.0) | (0.218)* | |
| Involved in tissue invasion/penetration | |||||
| ssp | 46 (86.8) | 23 (82.1) | 23 (92.0) | 0.425 (0.515) | |
| sak | 45 (84.9) | 21 (75.0) | 24 (96.0) | 3.054 (0.081) | |
| Involved in persistence | |||||
| icaA | 43 (81.1) | 21 (75.0) | 22 (88.0) | 0.733 (0.392) | |
| icaD | 53 (100) | 28 (100) | 25 (100) | NA | |
| Others | |||||
| sarA | 46 (86.8) | 24 (85.7) | 22 (88.0) | 0.000 (1.000) | |
| efb | 40 (75.5) | 18 (64.3) | 22 (88.0) | 4.012 (0.045) | |
| ACME-arcA | 0 | 0 | 0 | NA | |
P<0.05 were considered statistically significant.
NA, not available.
*
Fisher’s exact test.