Table 3. Distribution of 35 virulence genes among the isolates of MuH MRSA from Shanghai and Wenzhou, China.
Gene | No. of isolates positive for the gene [% of total (n = 53)] | No.of isolates positive for the gene in two regions (%) | χ2 (P value) | ||
Shanghai (n = 28) | Wenzhou (n = 25) | ||||
Involved in toxin mediated disease and/or sepsis | |||||
sea | 29 (54.7) | 9 (32.1) | 20 (80.0) | 12.208 (<0.001) | |
seb | 0 | 0 | 0 | NA | |
sec | 12 (22.6) | 12 (42.9) | 0 | 13.850 (<0.001) | |
sed | 0 | 0 | 0 | NA | |
see | 0 | 0 | 0 | NA | |
seg | 20(37.7) | 16 (57.1) | 4 (16.0) | 9.515 (0.002) | |
seh | 0 | 0 | 0 | NA | |
sei | 15 (28.3) | 15 (53.6) | 0 | 18.680 (<0.001) | |
sej | 2 (3.8) | 2 (7.1) | 0 | (0.492)* | |
tst | 14 (26.4) | 14 (50.0) | 0 | 16.987 (<0.001) | |
eta | 0 | 0 | 0 | NA | |
etb | 0 | 0 | 0 | NA | |
hla | 52 (98.1) | 27 (96.4) | 25 (100) | (1.000)* | |
hlb | 43 (81.1) | 21 (75.0) | 22 (88.0) | 0.733 (0.392) | |
hld | 0 | 0 | 0 | NA | |
Involved in attachment | |||||
fnbA | 48 (90.6) | 26 (92.9) | 22 (88.0) | 0.018 (0.894) | |
fnbB | 8 (15.1) | 7 (25.0) | 1 (4.0) | 3.045 (0.081) | |
clfA | 41 (77.4) | 21 (75.0) | 20 (80.0) | 0.189 (0.664) | |
clfB | 52 (98.1) | 27 (96.4) | 25 (100) | (1.000)* | |
cna | 42 (79.2) | 19 (67.9) | 23 (92.0) | 4.681 (0.031) | |
bbp | 7 (13.2) | 6 (21.4) | 1 (4.0) | 2.145 (0.143) | |
ebpS | 50 (94.3) | 27 (96.4) | 23 (92.0) | 0.010 (0.919) | |
Involved in evading/destroying host defenses | |||||
pvl | 8 (15.1) | 8 (28.6) | 0 | 6.331 (0.012) | |
hlg | 46 (86.8) | 22 (78.6) | 24 (96.0) | 2.145 (0.143) | |
hlgv | 7 (13.2) | 6 (21.4) | 1 (4.0) | 2.145 (0.143) | |
cap-5 | 0 | 0 | 0 | NA | |
cap-8 | 48 (90.6) | 23 (82.1) | 25 (100) | 3.061 (0.080) | |
map | 44 (83.0) | 23 (82.1) | 21 (84.0) | 0.000 (1.000) | |
sbi | 51 (96.2) | 28 (100) | 23 (92.0) | (0.218)* | |
Involved in tissue invasion/penetration | |||||
ssp | 46 (86.8) | 23 (82.1) | 23 (92.0) | 0.425 (0.515) | |
sak | 45 (84.9) | 21 (75.0) | 24 (96.0) | 3.054 (0.081) | |
Involved in persistence | |||||
icaA | 43 (81.1) | 21 (75.0) | 22 (88.0) | 0.733 (0.392) | |
icaD | 53 (100) | 28 (100) | 25 (100) | NA | |
Others | |||||
sarA | 46 (86.8) | 24 (85.7) | 22 (88.0) | 0.000 (1.000) | |
efb | 40 (75.5) | 18 (64.3) | 22 (88.0) | 4.012 (0.045) | |
ACME-arcA | 0 | 0 | 0 | NA |
P<0.05 were considered statistically significant.
NA, not available.
Fisher’s exact test.