Table 2. Biological processes of the differentially-regulated miRNAs.
| Biological Process | Genes (REF) | Targets of miRNAs | |||
| # | # | expected | +/− | P value | |
| Up-regulated miRNAs | |||||
| Primary metabolic process | 9122 | 878 | 572.72 | + | 1.72E-53 |
| Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 4156 | 499 | 260.93 | + | 1.01E-48 |
| Metabolic process | 9603 | 891 | 602.92 | + | 2.48E-47 |
| Cellular process | 7133 | 717 | 447.84 | + | 4.55E-46 |
| Developmental process | 3296 | 405 | 206.94 | + | 2.00E-40 |
| Intracellular signaling cascade | 1720 | 237 | 107.99 | + | 2.41E-29 |
| Signal transduction | 4858 | 488 | 305.00 | + | 6.88E-28 |
| System development | 2222 | 277 | 139.51 | + | 1.16E-27 |
| Cell communication | 5033 | 500 | 315.99 | + | 1.33E-27 |
| Cell cycle | 2018 | 255 | 126.70 | + | 3.38E-26 |
| Down-regulated miRNAs | |||||
| Cellular process | 7133 | 1658 | 1031.06 | + | 9.47E-106 |
| Primary metabolic process | 9122 | 1967 | 1318.57 | + | 3.78E-103 |
| Metabolic process | 9603 | 2000 | 1388.10 | + | 5.14E-91 |
| Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 4156 | 1034 | 600.74 | + | 2.25E-71 |
| Developmental process | 3296 | 857 | 476.43 | + | 2.24E-65 |
| Cell communication | 5033 | 1152 | 727.51 | + | 2.84E-61 |
| Signal transduction | 4858 | 1101 | 702.22 | + | 8.56E-56 |
| Intracellular signaling cascade | 1720 | 509 | 248.62 | + | 9.15E-52 |
| System development | 2222 | 606 | 321.19 | + | 8.21E-51 |
| Cell cycle | 2018 | 563 | 291.70 | + | 7.75E-50 |