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Effect of T-cell α7nAChR deficiency on suppression of endotoxin-induced TNF production in vitro. T cells from WT or α7nAChR-deficient mice were cocultured with T cell–depleted WT splenocytes, stimulated with endotoxin and TNF measured in the supernatant. Results are shown as median TNF in pg/mL (lower quartile–upper quartile). NT, T cell depleted; α70, α7nAChR KO.
