Figure 7.

MicroRNA 184 and 204 competitive RNA network during SC-associated EMT. Schematic diagram demonstrating binding patterns of SC-associated miRNAs to the 3′UTR of potential SC expressed target mRNAs. Target mRNAs are shown for mmu-miR-184 (A) and mmu-miR-204 (B) identified by TargetScan predictions followed by screening for potential SC-associated genes that play a role during EMT listed by the AmiGO gene ontology under the GO terms GO:0001837:epithelial to mesenchymal transition and GO:0002088: lens development in camera-type eye. MicroRNA 3′UTR binding sites are demonstrated in circles with numbers depicting the specific type of microRNA. SC-associated microRNA upregulation is indicated by red circles and downregulation by green circles. SC-associated target mRNA upregulation is in red and down-regulation is in green.