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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Biomaterials. 2012 Apr 20;33(21):5441–5450. doi: 10.1016/j.biomaterials.2012.03.077

Figure 2.

Figure 2

Specificity of PNB mediated cargo delivery. CD3-positive (a–c) and -negative (e–g) cells in suspension. Images of target (a–c) and non-target (e–g) cells: a,e: confocal bright field and optical scattering images show NP clusters (red) in cells; b,f: time-resolved optical scattering images show bright PNB in target cell; c,g: confocal fluorescent and bright field images obtained after the PNB treatment show FITC-Dextran dye in target cell (the insert shows the initial delivery localization of dye within 10 min after PNB generation). Optical scattering time-responses show PNB-specific signal for target cell (d) and no PNB for non-target cell (h), the PNB lifetime is measured as duration of PNB-specific signals.