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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Bioorg Med Chem. 2012 Jan 21;20(5):1671–1678. doi: 10.1016/j.bmc.2012.01.022

Scheme 6.

Scheme 6

Reagents and conditions: Method A: (1) KI, K2CO3, DME, reflux, 16 h; (2) TsOH, MeOH, rt. Method B: KI, K2CO3, DME, reflux, 16 h. Method C: K2CO3, DME, reflux, 16 h.