Table 1.
Clinicopathological characteristics and univariate analysis of 211 patients
| Characteristics | Total (n = 211) |
Bilateral PTMC (n = 54) |
Unilateral PTMC (n = 157) |
P value |
|---|---|---|---|---|
| Gender(M/F) |
32/179 |
8/46 |
24/133 |
0.934 |
|
Age ± SD (years) |
49 ± 11 |
49 ± 10 |
48 ± 11 |
0.679a |
| ≥45/<45 |
143/68 |
38/16 |
105/52 |
0.636 |
| ≥50/<50 |
97/114 |
23/31 |
74/83 |
0.564 |
|
Primary tumor size ± SD (mm) |
5.8 ± 2.7 |
6.8 ± 2.6 |
5.5 ± 2.7 |
0.001a,b |
| ≥5/<5 |
144/67 |
44/10 |
100/57 |
0.015 b |
| ≥7/<7 |
81/130 |
28/26 |
53/104 |
0.018 b |
| Multifocality (%) |
25 (11.8) |
21 (38.9) |
4 (2.6) |
<0.001b |
| ETE (%) |
10 (4.7) |
5 (9.3) |
5 (3.2) |
0.128c |
| T stage (T1/2:T3/4) |
201/10 |
49/5 |
152/5 |
0.128c |
| With HT (%) |
59 (28.0) |
20 (37.0) |
39 (24.8) |
0.085 |
|
Preoperative tumor size (mm) |
6.1 ± 2.9 |
7.1 ± 2.7 |
5.8 ± 2.8 |
0.005a,b |
| ≥5/<5 |
152/59 |
46/8 |
106/51 |
0.013 b |
| ≥7/<7 |
85/126 |
29/25 |
56/101 |
0.020 b |
| Preoperative multifocality (%) | 19 (8.6) | 16 (29.6) | 3 (1.9) | <0.001b,c |
aCalculated using two-tailed student t test.
bStatistically significant (P <0.05).
cCalculated using Fisher exact test, others calculated using chi-square test.
ETE, extrathyroidal extension; HT,Hashimoto thyroiditis; PTMC, papillary thyroid microcarcinoma.