Fig. 2.

Map-based cloning of SOR1. (A) Localization of the sor1 mutation to a 200-kb region on the long arm of chromosome VII. The position of established molecular markers as well as newly designed markers within the region of 1,100–1,500 kb chromosome VII and the number of recombinants for each marker are indicated. (B) Location of a C to T transition at position 3,263 bp relative to the translation start codon within the ninth exon of the 3,333-bp SOR1 gene. (C) Amino acid sequence (one letter code) of the corresponding SOR1 protein with the change of proline 371 into a leucine in the sor1 mutant indicated by an arrow. The positions of amino acids of the predicted bZIP DNA binding domain are underlined.