Table 1.
Expression overlap with previously identified TB-related signatures
| Differentially expressed genes† |
|||||
| Signature (reference) | Unique gene IDs | No. of annotated genes* | TB | SARC | Overlap‡ (%) |
| 393 transcript TB signature (3) | 312 | 291 | 219 (75%) | 221 (76%) | 89 |
| 86 transcript TB-specific signature (3) | 79 | 75 | 58 (77%) | 63 (84%) | 98 |
| IFN signaling (ingenuity) | 30 | 28 | 21 (75%) | 21 (75%) | 90 |
| IFN-inducible (module M3.1) (10) | 93 | 90 | 70 (78%) | 65 (72%) | 91 |
Differentially expressed genes in patients vs. healthy controls in previously identified TB-related signatures.
*Number of genes containing annotations on the Agilent platform used in this study.
†Number of differentially expressed genes at q < 0.01 between TB or SARC patients and healthy controls (percentage of differentially expressed genes of total annotated in parentheses).
‡Percentage of differentially expressed genes in both diseases.