Table 2.
Expression overlap with previously identified biological pathways
| Differentially expressed genes* |
|||||
| Pathway (reference) | KEGG ID | Annotated genes/pathway | TB | SARC | Overlap† (%) |
| TB | hsa05152 | 172/180 | 118 (69%) | 116 (67%) | 90 |
| Systemic lupus erythematosus (6) | hsa05322 | 121/138 | 78 (64%) | 81 (67%) | 85 |
| Complement and coagulation cascades (6) | hsa04610 | 68/69 | 31 (46%) | 32 (47%) | 68 |
| Toll-like receptor signaling pathway (6) | hsa04620 | 96/102 | 69 (72%) | 79 (82%) | 93 |
| Fc γ-receptor–mediated phagocytosis (6) | hsa04666 | 92/95 | 67 (73%) | 71 (77%) | 93 |
Differentially expressed genes in patients vs. healthy controls in previously identified biological pathways.
*Number of differentially expressed genes at q < 0.01 between TB or SARC patients and healthy controls (percentage of differentially expressed genes of total annotated in parentheses).
†Percentage of differentially expressed genes in both diseases.