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. 2012 May 1;109(20):7899–7904. doi: 10.1073/pnas.1201997109

Fig. 1.

Fig. 1.

EGFP-tagged TRIP8b-1a bound to HCN2 channels regulates their voltage dependence. (A) Cartoon showing the isoform TRIP8b-1a used in this study. (B) Current families from cell-attached patches on oocytes that expressed HCN2 alone and HCN2 with EGFP-TRIP8b-1a. (C) Conductance-voltage relationship for HCN2 channels and HCN2 channels with EGFP-TRIP8b-1a measured in the cell-attached patch configuration. (D) Confocal microscopy images of oocytes expressing EGFP-TRIP8b-1a alone and EGFP-TRIP8b-1a coexpressed with HCN2 channels.