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A: Western blot at day 14 demonstrates significantly more JNK1 protein in male elastase (ME) compared to female elastase (FE) (p=0.033). Also significantly more JNK1 and JNK2 protein in male elastase treated animals (ME) compared to control (MC) (p=0.0035 and p=0.0328, respectively). B: Zymography reveals significantly more proMMP9 (p=0.03), proMMP2 (p=0.0009), and active MMP2 (p=0.0112) in the elastase treated males compared to females at day 14.
