Table 2.

 Meta-analysis of effect of tranexamic acid on risk of blood transfusion, stratified by type of surgery

Type of surgery	No of events (tranexamic acid/control)	Pooled risk ratio (95% CI)	P value*	Heterogeneity
				Cardiac	622/835	0.65 (0.60 to 0.70)	<0.001	60	<0.001
Orthopaedic	298/462	0.55 (0.49 to 0.61)	<0.001	83	<0.001
Hepatic	29/54	0.52 (0.39 to 0.68)	<0.001	93	<0.001
Urological	40/60	0.66 (0.48 to 0.91)	0.01	2	0.31
Vascular	11/19	0.58 (0.34 to 0.99)	0.05	—	—
Gynaecological	17/50	0.86 (0.48 to 1.54)	0.61	65	0.06
Cranial and orthognathic	52/76	0.63 (0.45 to 0.86)	0.004	46	0.12

*Test for effect.