Table 1.
logEstradiol (E2) rates of change in the time from 2 years before final menstrual period (FMP) to FMP, by CYP19 rs749292 and CYP19 rs9363062
Genotype | Number of women | Genotype slopes (β, pg/ml) | Slope as a proportion of the fastest rate of decline (%) |
---|---|---|---|
CYP19 rs749292 | |||
AA | 143 | −0.0482 | 96 |
AG | 328 | −0.0501 | 100 (referent) |
GG | 200 | −0.0337* | 67 |
CYP19 rs9363062 | |||
CC | 356 | −0.0543 | 92 |
CT | 230 | −0.0318* | 54 |
TT | 89 | −0.0591 | 100 (referent) |
Genotype slope is statistically different than other genotype slopes, P < 0.05.