Skip to main content
. Author manuscript; available in PMC: 2012 May 21.
Published in final edited form as: Clin Endocrinol (Oxf). 2011 May;74(5):618–623. doi: 10.1111/j.1365-2265.2010.03968.x

Table 3.

logEstradiol (E2) rates of change as slopes according to obesity classification (BMI<30 vs BMI>30) and type 1 17β hydroxysteroid dehydrogenase (17β HSD) rs615942 genotypes

Type 1 17β HSD rs615942
Number of women Slopes (β, pg/ml) Slope as a proportion of the fastest rate of decline (%) Slope as a proportion of the rate of decline within obesity group (%)
BMI < 30 kg/m2
 GG 129 −0.0619* 71 71
 TG 219 −0.0866*† 100 (referent) 100 (referent)
 TT 106 −0.0549* 63 63
BMI ≥ 30 kg/m2
 GG 65 −0.0179† 21 42
 TG 98 −0.0426† 49 100 (referent)
 TT 59 −0.0109 13 26
*

Within genotype, BMI<30 group declines faster than BMI>30, P < 0.01.

†

Genotype slope is significantly different than other genotype slopes within the obesity group.