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. 2010 Sep;8(3):155–164. doi: 10.1089/lrb.2010.0004

FIG. 2.

FIG. 2.

(A) ECAM expression in SV-LEC. ICAM-1. TNF-α (20 ng/ml) induced ICAM-1 over untreated controls; IL-1β (10 ng/ml) and IFN-γ (1000 U/ml) induced ICAM-1. VCAM-1. TNF-α (20 ng/ml) and IL-1β (10 ng/ml) and IFN-γ (1000 U/ml) induced VCAM-1. MAdCAM-1. TNF-α (20 ng/ml) significantly induced MAdCAM-1 expression. Neither IL-1β, nor IFN-γ induced MAdCAM-1. E-Selectin. Only IFN-γ (1000 U/ml) induced E-selectin on LEC. TNF-α (20 ng/ml) or IL-1β (10 ng/ml) slightly, (n.s.) increased E-selectin. (B) HMEC-1a ECAM expression. ICAM-1. TNF-α (20 ng/ml), IL-1β (10 ng/ml), and IFN-γ (1000 U/ml) each induced ICAM-1. VCAM-1. TNF-α (20 ng/ml), IL-1β (10 ng/ml) but not IFN-γ (1000 U/ml) induced VCAM-1. E-selectin. IL-1β and TNF-α induced E-Selectin on HMEC-1a cells.