Table 2. Demographic and clinical characteristics of DSA+ and DSA– study patients, and of the general liver transplant recipients.
| General liver transplants n = 896 | p-Value1 | DSA+ n = 27 | DSA– n = 16 | p-Value2 | |
|---|---|---|---|---|---|
| Age (years) | 54 | NS | 46 | 51 | NS |
| Gender female/ male | 364/532 | NS | 10/17 | 11/5 | NS |
| EthnicityCaucasian/ | 830/19/47 | NS | 27/0/0 | 14/1/1 | NS |
| African American/Other | – | – | – | – | – |
| Donor type | – | NS | – | – | NS |
| DBD | 830 | – | 20 | 15 | – |
| DCD | 55 | – | 5 | 1 | – |
| LRL | 10 | – | 1 | 0 | – |
| LUL | 1 | – | 1 | 0 | – |
| Etiology of original disease | NS | NS | |||
| Alcohol | 269 | – | 5 | 4 | – |
| HCV | 162 | – | 4 | 2 | – |
| PSC/PBC | 96/60 | – | 6/0 | 1/2 | – |
| NASH | 94 | – | 3 | 2 | – |
| Cryptogenic cirrhosis | 43 | – | 2 | 0 | – |
| α-1 Antitrypsin deficiency | 29 | – | 2 | 2 | – |
| Autoimmune hepatitis | 31 | – | 1 | 2 | – |
| Biliary atresia | 31 | – | 1 | 0 | – |
| Fulminant liver failure | 18 | – | 1 | 0 | – |
| Wilson's disease | 11 | – | 1 | 0 | – |
| Idiopathic ductopenia | 1 | – | 1 | 0 | – |
| Fibrolamellar HCC | 0 | – | 0 | 1 | – |
| Other | 94 | – | – | – | – |
| Liver tests | |||||
| TBIL (0–1.4 mg/dL) | – | – | 5.8 ± 6.5 | 6.0 ± 6.7 | NS |
| ALT (0–65 U/L) | – | – | 314 ± 224 | 349 ± 344 | NS |
| ALKP (35–130 U/L | – | – | 368 ± 200 | 398 ± 397 | NS |
| GGT (0–85 U/L) | – | – | 654 ± 495 | 580 ± 722 | 0.055 |
1
General liver transplant recipients ≥15 years of age during the study period at our institution versus study population.
2
DSA+ versus DSA- study patients.
TBIL = total bilirubin; ALT = alanine aminotransferase; ALKP = alkaline phosphatase; GGT = gamma glutamyltranspeptidase.