Table 4. Association of C4d staining patterns with acute cellular rejection, overall and in conjunction with DSA.
C4d | ACR+ | ACR− | p Value |
---|---|---|---|
Diffuse portal C4d+ | 68% (19/28) | 27% (4/15) | 0.01* |
Diffuse portal C4d+ DSA+ | 53% (15/28) | 15% (2/15) | 0.02* |
Focal portal C4d+ | 67% (6/9) | 46% (5/11) | 0.41 |
Focal portal C4d+ DSA+ | 33% (3/9) | 9% (1/11) | 0.28 |
Portal vein E C4d+ | 61% (17/28) | 47% (7/15) | 0.52 |
Portal vein E C4d+ DSA+ | 36% (10/28) | 20% (3/15) | 0.49 |
Sinusoidal E C4d+ | 38% (12/28) | 13% (2/15) | 0.16 |
Sinusoidal E C4d+ DSA+ | 25% (7/28) | 0% (0/15) | 0.08 |
E = endothelium.