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. Author manuscript; available in PMC: 2013 May 16.
Published in final edited form as: J Am Chem Soc. 2012 May 7;134(19):8050–8053. doi: 10.1021/ja302197x

Figure 2.

Figure 2

Exponential amplification of d- (squares) and l-(circles) self-replicating RNA enzymes. The yield of E was determined at various times and the data were fit to the logistic growth equation: [E] = a / (1 + be−c t), where a is the final extent, b is the degree of sigmoidicity, and c is the exponential growth rate. Reaction conditions: 2.5 µM A, 20 µM B, either 0.36 µM d-E or 0.25 µM l-E, 25 mM MgCl2, pH 8.5, 42 °C.