Prevalence of CBD103 common variant and gene copy-number variation. a Pie graphs represent individuals of a given breed, divided into canine genotypes: CBD103/CBD103 (blue), CBD103/CBD103ΔG23 (yellow) and CBD103ΔG23/CBD103ΔG23 (red). Doberman Pinschers (n = 15), German Shepherds (n = 15) and Rottweilers (n = 15) do not appear to have the CBD103ΔG23 allele, whereas Golden retrievers (n = 13) and Labrador retrievers (n = 16) possess the CBD103ΔG23 allele as a heterozygote or homozygote variant. b Plot of CBD103 gene copy-number variation with colors indicating the CBD103 genotype. Doberman Pinschers, German Shepherds and Rottweilers encode 2 copies of CBD103 per diploid genome, whereas Golden retrievers and Labrador retrievers have variation in their total CBD103 gene copy number.