FIG. 2.

Immature cerebral microvessels are more abundant in diabetes. A: Diabetic group had significantly increased cortical and striatal nonperfused vessels compared with controls. B: Pericyte-to-endothelial ratio was decreased in the diabetic group. C: There was a visual but not statistically significant increase in retinal vasculature, whereas peripheral vasculature was decreased in diabetes. *P = 0.0016 diabetes vs. control; ψP = 0.01; **P = 0.029 diabetes vs. control. Data are means ± SEM, n = 3–4 (exact Wilcoxon test).