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Increased VEGF expression and tyrosine nitration status of micro- and macrovasculature in diabetes. A: VEGF levels were significantly increased in the cerebral microvasculature but not the macrovasculature in diabetes. B: Both diabetic micro- and macrovasculature had significantly increased tyrosine nitration compared with controls. *P = 0.001; **P = 0.05 diabetes vs. control. Data are means ± SEM, n = 4 (exact Wilcoxon test).
