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. 2012 May 14;61(6):1543–1551. doi: 10.2337/db11-1152

FIG. 4.

FIG. 4.

Loss of Est inhibited DEX- and HFD-induced insulin intolerance. A: GTT in WT and Est−/− female mice treated with vehicle or DEX (daily i.p. injection at 1 mg/kg) for 2 weeks. B: Hepatic Est expression in DEX or vehicle-treated WT female C57BL/6J mice. C: GTT in WT and Est−/− male mice treated with vehicle or DEX. D: GTT and ITT in WT and Est−/− female mice fed with HFD for 20 weeks. E: Hepatic Est expression in WT female C57BL/6J mice fed with HFD for 20 weeks. N = 5 for each group. *P < 0.05; **P < 0.01.