Table 2.

The Effect of MnTnHex-2-PyP⁵⁺ Treatment on the Growth of Subcutaneous Human Brain Tumor Xenografts in Mice. MnTnHex-2-PyP⁵⁺ was given sc at a dose of 1.6 mg/kg b.i.d. throughout the duration of experiment. T-C, is defined as the difference in days between the median time required for tumors in treated (T) and control (C) animals to reach a volume five times greater than that measured at the start of treatment

Xenograft	Histology	Adult/Pediatric	In Vivo Results
			T-C (days)	P Value	Regressions
D-54 MG	Glioblastoma multiforme	Adult	3	≤0.345	0/10
D-245 MG	Glioblastoma multiforme	Adult	11	≤0.001	1/10
D-256 MG	Glioblastoma multiforme	Adult	4.3	≤0.001	0/10
D-341 MED	Medulloblastoma	Pediatric	34	≤0.001	10/10
D-456 MG	Glioblastoma multiforme	Pediatric	21.3	≤0.001	10/10