Table 3. Median total cholesterol, HDL, LDL and triglyceride concentrations [mmol/L] in with 25%- and 75%-quantiles stratified by FADS genotype (A: major allele/ a: minor allele).

	Total cholesterol	HDL	LDL	Triglyceride
rs174545
AA	4.81 (4.29,5.34)	1.27 (1.06,1.47)	2.13 (1.74,2.57)	1.14 (0.87,1.57)
Aa	4.77 (4.28,5.30)	1.23 (1.06,1.42)	2.13 (1.74,2.51)	1.23 (0.93,1.67)
aa	4.68 (4.18,5.16)	1.26 (1.09,1.43)	2.01 (1.67,2.47)	1.23 (0.92,1.69)
p-value1	0.1189	0.2246	0.0718	0.0058
rs174546
AA	4.82 (4.29,5.34)	1.27 (1.07,1.47)	2.13 (1.74,2.57)	1.14 (0.88,1.57)
Aa	4.77 (4.28,5.31)	1.23 (1.06,1.42)	2.13 (1.74,2.51)	1.24 (0.94,1.68)
aa	4.66 (4.18,5.15)	1.26 (1.09,1.43)	2.01 (1.67,2.47)	1.22 (0.92,1.68)
p-value1	0.0793	0.1494	0.0701	0.0078
rs174556
AA	4.83 (4.30,5.38)	1.27 (1.07,1.47)	2.14 (1.74,2.58)	1.15 (0.88,1.58)
Aa	4.76 (4.28,5.30)	1.23 (1.06,1.41)	2.12 (1.73,2.49)	1.23 (0.94,1.69)
aa	4.65 (4.18,5.08)	1.25 (1.09,1.43)	1.98 (1.65,2.38)	1.22 (0.90,1.68)
p-value1	0.0263	0.0842	0.0182	0.0071
rs174561
AA	4.83 (4.30,5.38)	1.27 (1.07,1.47)	2.14 (1.74,2.59)	1.15 (0.88,1.58)
Aa	4.76 (4.28,5.29)	1.23 (1.06,1.42)	2.12 (1.73,2.49)	1.23 (0.94,1.69)
aa	4.65 (4.18,5.11)	1.25 (1.09,1.43)	2.00 (1.65,2.38)	1.25 (0.92,1.68)
p-value1	0.0288	0.1042	0.0145	0.0076
rs174575
AA	4.80 (4.28,5.32)	1.26 (1.06,1.46)	2.12 (1.73,2.53)	1.15 (0.88,1.57)
Aa	4.80 (4.31,5.35)	1.23 (1.06,1.43)	2.16 (1.75,2.54)	1.25 (0.93,1.72)
aa	4.63 (4.18,5.08)	1.24 (1.04,1.41)	1.96 (1.68,2.36)	1.24 (0.98,1.70)
p-value1	0.0390	0.3346	0.0325	0.0032
rs3834458
AA	4.81 (4.30,5.35)	1.26 (1.06,1.47)	2.13 (1.73,2.56)	1.15 (0.88,1.58)
Aa	4.79 (4.28,5.33)	1.23 (1.06,1.42)	2.16 (1.75,2.53)	1.24 (0.94,1.68)
aa	4.65 (4.23,5.14)	1.25 (1.06,1.43)	2.01 (1.68,2.40)	1.22 (0.94,1.69)
p-value1	0.0434	0.2505	0.0414	0.0081

¹p-value derived from Kruskal-Wallis rank sum test. Significance level after correction for multiple testing: α_corr = 0.025. Values reaching significance after adjustment for multiple testing are highlighted in bold.