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. 2012 May 21;7(5):e37412. doi: 10.1371/journal.pone.0037412

Table 3. Concentrations of urinary 1-OHPG, 8-OHdG and DNA strand breaks in the exposed and reference groups by order of day.

Exposed group Reference group
Variables 1st day 2nd day p-valuea 1st day 2nd day p-valueb p-valuec p-valued
Median(Q25-Q75) N Median(Q25-Q75) N Median(Q25-Q75) N Median(Q25-Q75) N
Biomarker of exposure
Urinary 1-OHPG (µg/g creatinine) 0.36 (0.21–0.58) 83 0.33 (0.17–0.55) 81 0.393 0.16 (0.08–0.23) 47 0.18 (0.11–0.31) 46 0.634 <0.001 0.001
Biomarkers of effect
Urinary 8-OHdG (µg/g creatinine) 3.67 (2.72–5.01) 87 3.44 (2.66–4.30) 83 0.494 2.53 (1.58–3.59) 47 2.28 (1.53–3.50) 46 0.133 <0.001 <0.001
DNA strand breaks (%) 14.95 (12.65–18.53) 89 15.37 (12.85–19.63) 82 0.314 9.26 (7.64–10.62) 49 9.46 (8.02–11.20) 47 0.536 <0.001 <0.001
a

Wilcoxon Signed rank test within exposed group.

b

Wilcoxon Signed rank test within reference group.

c

Mann-Whitney U test between exposed and reference group for the first day.

d

Mann-Whitney U test between exposed and reference group for the second day.