Table 3. Concentrations of urinary 1-OHPG, 8-OHdG and DNA strand breaks in the exposed and reference groups by order of day.
Exposed group | Reference group | |||||||||||
Variables | 1st day | 2nd day | p-valuea | 1st day | 2nd day | p-valueb | p-valuec | p-valued | ||||
Median(Q25-Q75) | N | Median(Q25-Q75) | N | Median(Q25-Q75) | N | Median(Q25-Q75) | N | |||||
Biomarker of exposure | ||||||||||||
Urinary 1-OHPG (µg/g creatinine) | 0.36 (0.21–0.58) | 83 | 0.33 (0.17–0.55) | 81 | 0.393 | 0.16 (0.08–0.23) | 47 | 0.18 (0.11–0.31) | 46 | 0.634 | <0.001 | 0.001 |
Biomarkers of effect | ||||||||||||
Urinary 8-OHdG (µg/g creatinine) | 3.67 (2.72–5.01) | 87 | 3.44 (2.66–4.30) | 83 | 0.494 | 2.53 (1.58–3.59) | 47 | 2.28 (1.53–3.50) | 46 | 0.133 | <0.001 | <0.001 |
DNA strand breaks (%) | 14.95 (12.65–18.53) | 89 | 15.37 (12.85–19.63) | 82 | 0.314 | 9.26 (7.64–10.62) | 49 | 9.46 (8.02–11.20) | 47 | 0.536 | <0.001 | <0.001 |
Wilcoxon Signed rank test within exposed group.
Wilcoxon Signed rank test within reference group.
Mann-Whitney U test between exposed and reference group for the first day.
Mann-Whitney U test between exposed and reference group for the second day.