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Luciferase reporter constructs, each containing one fragment of the IL11 3′ UTR, were co-transfected with a Renilla luciferase construct and the miRNA precursors into MDA-MB-231(SA) cells (n = 5), and luciferase activity was measured 28 hours later. * p<0.05, ** p<0.01, *** p<0.001, as compared to the negative control Pre-miR.
