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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Arch Ophthalmol. 2012 Jun;130(6):749–755. doi: 10.1001/archophthalmol.2011.2560

Table 2.

Univariate Relationship of Change in Central Retinal Arteriolar and Venular Equivalents to Incidence and Progression of Diabetic Retinopathy and Incidence of Macular Edema and Proliferative Diabetic Retinopathy.

Vessel Measurement N at Risk N of Events Odds Ratio 95% CI P value
Change in CRAE (per 10 μm)
 Incidence of DR 663 370 1.13 0.97, 1.32 0.13
 Progression of DR 1968 761 1.07 0.97, 1.18 0.15
 Incidence of ME 1885 199 1.10 0.96, 1.26 0.16
 Incidence of PDR 1968 297 0.89 0.78, 1.03 0.11
Change in CRVE (per 10 μm)
 Incidence of DR 665 373 1.14 1.01, 1.28 0.03
 Progression of DR 1963 761 1.13 1.05, 1.22 <0.001
 Incidence of ME 1884 197 1.20 1.09, 1.32 <0.001
 Incidence of PDR 1963 296 1.17 1.05, 1.31 0.004

CI, confidence interval; CRAE, central retinal arteriolar equivalent; CRVE, central retinal venular equivalent; DR, diabetic retinopathy; ME, macular edema; PDR, proliferative diabetic retinopathy.