Table 3.

Expected age-related bladder capacity and interpretation of maximum and total voided volume overnight (all in milliliters), EBC calculated as: [30 + (age in years × 30)] in milliliters

Age (years)	BC (ml)	MVV below listed volume = reduced bladder capacity; consider alarm	Total volume below listed value = nocturnal polyuria; consider desmopressin
5	180	117	234
6	210	137	273
7	240	156	312
8	270	176	351
9	300	195	390
10	330	215	429
11	360	234	468
12	390	254	507
13	390	254	507
14	390	254	507
15	390	254	507
16	390	254	507
17	390	254	507
18	390	254	507

A pronounced nocturnal arginine vasopressin deficiency is seen in desmopressin responders only on nights with enuresis—therefore, NP should only be looked for on wet nights [41]. Excessive nocturnal urinary volumes indicated by diary data and various additional signs are suggestive of underlying NP [43, 62], e.g., absorbent underpants totally soaked overnight, urine soaking through to the bedsheets, multiple episodes of wetting in one night, early wetting in the first third of the night, a large volume of urine at the first void in the morning despite wetting overnight, a low daytime fluid intake followed by the majority of the intake in the late afternoon and evening

MVV maximum voided volume, EBC expected bladder capacity, NP nocturnal polyuria