Table 1.
Multiple QTL models
Trait | Effect | Peak marker | LOD | %Variance | F | P |
---|---|---|---|---|---|---|
Hypothermia | ||||||
3@80.2 | rs3710548 | 3.607 | 4.272 | 4.131 | 0.002788 | |
7@18.4 | rs13479153 | 2.561 | 3.011 | 5.824 | 0.003261 | |
16@30.9 | rs4182243 | 2.708 | 3.188 | 6.166 | 0.002345 | |
Sex | 4.167 | 4.953 | 6.387 | 0.000321 | ||
3@80.2:sex | 3.039 | 3.586 | 6.935 | 0.001119 | ||
LORR | ||||||
Sex | 24.293 | 25.7219 | 8.0809 | 2.55E − 15 | ||
2@21.4 | rs13476399 | 6.785 | 6.3172 | 2.4808 | 0.00417 | |
4@93.4 | rs3695715 | 3.255 | 2.9549 | 3.4812 | 0.00849 | |
8@22.5 | rs3666140 | 3.595 | 3.2715 | 3.8542 | 0.00454 | |
12@31.0 | rs6344105 | 8.0043 | 7.5183 | 2.9525 | 0.00067 | |
19@33.8 | rs6194426 | 2.6302 | 2.3771 | 2.8005 | 0.02621 | |
sex:2@21.4 | 5.2937 | 4.8763 | 3.8299 | 0.00108 | ||
sex:4@93.4 | 0.4142 | 0.3685 | 0.8682 | 0.42076 | ||
sex:8@22.5 | 3.3885 | 3.079 | 7.2548 | 0.00084 | ||
sex:12@31.0 | 4.6929 | 4.3043 | 3.3806 | 0.00307 | ||
sex:19@33.8 | 2.432 | 2.1948 | 5.1715 | 0.0062 | ||
2@21.4:12@31.0 | 5.2204 | 4.8062 | 2.8311 | 0.00484 | ||
sex:2@21.4:12@31.0 | 4.3595 | 3.9889 | 4.6994 | 0.00109 | ||
BECs | ||||||
Sex | 2.39 | 2.889 | 3.571 | 0.014446 | ||
7@6.3 | rs13479145 | 4.899 | 6.029 | 3.726 | 0.001361 | |
9@11.6 | rs13480854 | 4.002 | 4.893 | 4.535 | 0.001422 | |
11@2.6 | rs3697686 | 5.317 | 6.563 | 4.056 | 0.000626 | |
sex:9@11.6 | 1.515 | 1.819 | 3.373 | 0.035568 | ||
7@6.3:11@2.6 | 2.58 | 3.122 | 2.894 | 0.022406 | ||
Rotarod averagea | ||||||
Sex | 3.336 | 3.379 | 4.965 | 0.002203 | ||
1@92.7 | rs3700831 | 2.241 | 2.253 | 4.966 | 0.007503 | |
4@9.0 | rs13477617 | 3.774 | 3.834 | 8.45 | 0.000264 | |
5@2.8 | rs13478110 | 3.398 | 3.443 | 3.794 | 0.004952 | |
6@48.2 | rs6239023 | 3.74 | 3.798 | 8.37 | 0.000285 | |
7@48.4 | mCV23423763 | 2.633 | 2.655 | 5.85 | 0.003187 | |
12@64.5 | rs13481614 | 2.238 | 2.25 | 4.959 | 0.007556 | |
18@56.2 | rs4137441 | 1.879 | 1.884 | 4.153 | 0.016549 | |
sex:5@2.8 | 3.335 | 3.378 | 7.445 | 0.000688 | ||
Training index | ||||||
11@42.4 | rs13481076 | 3.417 | 4.434 | 0.000409 | ||
Ataxia | ||||||
sex | 0.9151 | 0.9477 | 3.898 | 0.049212 | ||
8@39.7 | rs3699406 | 9.6403 | 10.586 | 2.419 | 0.001172 | |
9@44.0 | rs3655717 | 10.2343 | 11.2837 | 2.578 | 0.000506 | |
17@20.2 | rs3672987 | 11.406 | 12.676 | 2.896 | 9.05E-05 | |
8@39.7:9@44.0 | 4.4048 | 4.6692 | 1.6 | 0.090041 | ||
8@39.7:17@20.2 | 6.0238 | 6.4552 | 2.212 | 0.011097 | ||
9@44.0:17@20.2 | 6.7097 | 7.2235 | 2.476 | 0.004152 | ||
8@39.7:9@44.0:17@20.2 | 3.9876 | 4.2152 | 2.167 | 0.029703 |
Effect sizes for the peak marker(s), LOD scores, F statistic, and degrees of freedom are given for dropping each term from the model
aDue to the large number of loci in the model, multilocus interactions were not tested extensively