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Negative regulation of TLR signaling by miRNA. miR-146 negatively regulates the expression of IRAK1, IRAK2, and TRAF6. miR-21 negatively regulates the expression of a IL-12 p35 subunit. miR-155 inhibits the expression of TAB2, RIP1, IKKε, SOCS-1, and TIRAP. miR-223 suppresses the expression of TLR4 and IKKα, and miR-9 inhibits the expression of an NF-κB p50 subunit.
