Table 3.
Treatment | LDL-R | HMG-CoAR | CYP7A1 | ACAT2 |
---|---|---|---|---|
No nuciferine | 1 | 1 | 1 | 1 |
Nuciferine: low dose | 1.86 ± 0.84** | 2.18 ± 0.26** | 0.94 ± 0.17 | 0.97 ± 0.24 |
Nuciferine: medium dose | 2.95 ± 0.25** | 2.58 ± 0.14** | 0.93 ± 0.26 | 0.95 ± 0.28 |
Nuciferine: high dose | 3.57 ± 1.01** | 2.96 ± 0.25** | 1.15 ± 0.31 | 0.78 ± 0.19** |
Atorvastatin | 5.83 ± 0.19** | 6.58 ± 0.28** | 1.29 ± 0.12* | 0.49 ± 0.33** |
Note: comparison with no-drug control group, *P < 0.05, **P < 0.01.