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. 2012 May 9;2012:928234. doi: 10.1155/2012/928234

Table 3.

The effects of nuciferine treatment on cholesterol metabolism in liver cells (mRNA analysis).

Treatment LDL-R HMG-CoAR CYP7A1 ACAT2
No nuciferine 1 1 1 1
Nuciferine: low dose 1.86 ± 0.84** 2.18 ± 0.26** 0.94 ± 0.17 0.97 ± 0.24
Nuciferine: medium dose 2.95 ± 0.25** 2.58 ± 0.14** 0.93 ± 0.26 0.95 ± 0.28
Nuciferine: high dose 3.57 ± 1.01** 2.96 ± 0.25** 1.15 ± 0.31 0.78 ± 0.19**
Atorvastatin 5.83 ± 0.19** 6.58 ± 0.28** 1.29 ± 0.12* 0.49 ± 0.33**

Note: comparison with no-drug control group, *P < 0.05, **P < 0.01.