Table 4.
Treatment | LDL-R | HMG-CoAR | CYP7A1 | ACAT2 |
---|---|---|---|---|
No hyperin | 1 | 1 | 1 | 1 |
Hyperin: low dose | 1.64 ± 0.27* | 2.18 ± 0.19** | 1.21 ± 0.18* | 1.03 ± 0.21 |
Hyperin: medium dose | 2.82 ± 0.36** | 3.29 ± 0.31** | 1.57 ± 0.22** | 0.65 ± 0.36** |
Hyperin: high dose | 2.66 ± 0.24** | 2.87 ± 0.25** | 1.06 ± 0.19 | 0.61 ± 0.29** |
Atorvastatin | 5.82 ± 0.27** | 6.48 ± 0.29** | 1.29 ± 0.45** | 0.49 ± 0.38** |
Note: comparison with no-drug control group, *P < 0.05, **P < 0.01.