Table 5.

The effects of chrysophanol treatment on cholesterol metabolism in liver cells (mRNA analysis).

Treatment	LDL-R	HMG-CoAR	CYP7A1	ACAT2
No chrysophanol	0.42 ± 0.07	0.41 ± 0.11	0.28 ± 0.07	0.64 ± 0.15
Chrysophanol: low dose	0.62 ± 0.04*	0.54 ± 0.19*	0.31 ± 0.12	0.42 ± 0.16**
Chrysophanol: medium dose	0.75 ± 0.03**	0.72 ± 0.14**	0.33 ± 0.09*	0.37 ± 0.18**
Chrysophanol: high dose	0.88 ± 0.09**	0.81 ± 0.22**	0.37 ± 0.14**	0.30 ± 0.07**
Atorvastatin	0.93 ± 0.07**	0.86 ± 0.18**	0.49 ± 0.13*	0.31 ± 0.13**

Note: comparison with no-drug control group, *P < 0.05, **P < 0.01.