Fig. 3.

Simplified risk/benefit based process of deriving quantitative human health management criteria for dioxins and PUFAs (polyunsaturated fatty acids) in fish (modified from Assmuth and Jalonen 2005), emphasizing multi-level influencing factors and uncertainties. Note that the different levels and types of uncertainty overlap. Those factors and criteria related only to PBTs have been shown by hatched lines. RR risk ratio (in epidemiological studies), DALYs disability-adjusted life years, TDI tolerable daily intake; ADI advisable daily intake