Fig.5.

Protection of neurons from rotenone and paraquat by GSH augmentation via pretreatment with NAC or by co-culture with astrocytes. Neurons were pretreated with 5mM NAC (fig. 5a and b) or co-cultured with astrocytes (fig. 5c and d) in the presence of varying concentrations of rotenone or paraquat for 4 h. % control refers to the number of trypan blue negative cells as a % on control values (0). Values are expressed as the mean±SEM. n=3. * denotes P<0.05, treated cells compared to control in fig 1a.