Table 5.
Talairach Coordinates for peak values | Area | BA | Volume (mm3) | t value for peak values | |
---|---|---|---|---|---|
HC | |||||
Angry vs. Neutral | |||||
Follow-up > Baseline | none | none | none | none | none |
Baseline > Follow-up | 26, 11, 2 | R putamen | 135 | 3.73 | |
5 -16 32 | R midcingulate gyrus | 24 | 135 | 3.67 | |
Happy vs Neutral | |||||
Follow-up > Baseline | 62, -43, 29 | R inferior parietal gyrus | 40 | 135 | 4.58 |
Baseline > Follow-up | none | none | none | none | none |
Risperidone Group | |||||
Angry vs. Neutral | |||||
Follow-up > Baseline | 11, -7, 29 | R midcingulate gyrus | 24 | 162 | 4.03 |
26, -13, -4 | R ventral striatum | 108 | 3.15 | ||
-12, -4, -2 | L ventral striatum | 108 | 4.74 | ||
Baseline > Follow-up | none | none | none | none | none |
Happy vs. Neutral | |||||
Follow-up > Baseline | none | none | none | none | none |
Baseline > Follow-up | none | none | none | none | none |
Divalproex Group | |||||
Angry vs. Neutral | |||||
Follow-up > Baseline | 20, 65, 5 | R medial frontal gyrus | 10 | 243 | 3.87 |
53, -34, -4 | R middle temporal gyrus | 21 | 108 | 4.24 | |
Baseline > Follow-up | none | none | none | none | none |
Happy vs. Neutral | |||||
Follow-up > Baseline | -46, 20, 14 | L inferior frontal gyrus | 45 | 108 | 3.24 |
Baseline > Follow-up | none | none | none | none | none |
Note: Talairach coordinates and t values for clusters for which there is a significant three-way interaction (corrected p<0.05, with cluster contiguity threshold) in the whole-brain Analysis of Variance (ANOVA). BA = Brodmann Area; HC=healthy control; L=left; R=right.