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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Genet Epidemiol. 2012 Mar 28;36(4):303–311. doi: 10.1002/gepi.21622

Figure 1.

Figure 1

Multilocus penetrance functions and allele frequencies (p, q) used to simulate case-control data exhibiting gene-gene interactions in absence of main effects. For each model, the marginal penetrances all equal the population disease frequency, KP.