Figure 2.

Preparation of QU-loaded MPEG-PCL nanoparticles. MPEG-PCL and QU were co-dissolved in organic solvent, followed by evaporation to dryness under reduced pressure in a rotary evaporator, creating QU and MPEG-PCL mixture (QU + MPEG-PCL).

Notes: The QU and MPEG-PCL mixture was then hydrated in 0.9% normal saline, allowing QU and MPEG-PCL to self-assemble into QU/MPEG-PCL micelles. This micelle has a core-shell structure (hydrophilic PEG shell and hydrophobic PCL core) with core-encapsulated QU.

Abbreviations: MPEG, monomethoxy poly(ethylene glycol); PCL, poly(ɛ-caprolactone); QU, quercetin.