Table 1.
Formulation of polymeric gemcitabine microparticulates with chitosan
Formula number | Chitosan (mg) | Yield (%) | Drug loading (%) | Entrapment efficiency (%) |
---|---|---|---|---|
F10 | 0 | 86.4 | 1.8 | 33.4 |
F49 | 10 | 86.4 | 1.7 | 33.9 |
F50 | 25 | 91.7 | 5.8 | 93.7 |
F51 | 50 | 80.8 | 5.0 | 88.7 |
F52 | 100 | 100.8 | 4.5 | 97.9 |
F53 | 150 | 99.5 | 4.7 | 93.0 |