Table 5.

AUC values of emodin in various formulations (μg · min/mL, μg · min/g)

Formulations	Plasma	Heart	Liver	Spleen	Lung	Kidney
Free emodin	69.79	48.04	332.90	40.65	37.30	132.68
TPGS liposomal emodin	122.02	145.85	411.42	55.10	275.53	540.30
mPEG2000–DSPE liposomal emodin	133.74	109.40	435.85	50.16	81.06	278.20

Abbreviations: AUC, area under the emodin concentration versus time curve; μg, microgram; min, minute; mL, milliliter; g, gram; TPGS, D-α-tocopheryl polyethylene glycol 1000 succinate; mPEG2000–DSPE, methoxypolyethyleneglycol 2000-derivatized distearoyl-phosphatidylethanolamine.