Table 3. Sensitivity of UKF-NB-3 cells, UKF-NB-3^rNutlin^10 μM cells, UKF-NB-3^rNutlin^10 μM cells transduced with a lentiviral vector encoding wild-type p53 (UKF-NB-3^rNutlin^{10 μMwtp53}), and UKF-NB-3^rNutlin^10 μM cells transduced with a control vector (UKF-NB-3^rNutlin^{10 μMcontrol}) to RITA or nutlin-3 indicated by the concentration that reduces cell viability by 50% (IC₅₀) indicated by MTT assay after a 5 day treatment period.

Cell line	RITA ( μM)	Nutlin-3 ( μM)
UKF-NB-3	0.11±0.02	1.47±0.15
UKF-NB-3rNutlin10 μM	0.62±0.04	32.83±2.91
UKF-NB-3rNutlin10 μMwtp53	0.24±0.03	5.02±1.73
UKF-NB-3rNutlin10 μMcontrol	0.58±0.03	36.19±3.08