Table 4. Numbers of genes differentially expressed relative to UKF-NB-3 (false discovery rate (FDR)<0.05 or <0.01 after correction for multiple testing) in RITA- or nutlin-3-adapted UKF-NB-3 sub-lines as determined by microarray measurement of mRNA abundance.
| Comparison UKF-NB-3 versus | Differentially expressed genes (FDR<0.05) | Differentially expressed genes (FDR<0.01) |
|---|---|---|
| All sub-lines | 1360 | 520 |
| All RITA-resistant sub-lines | 1495 | 676 |
| All nutlin-3-resistant sub-lines | 6465 | 4090 |
| UKF-NB-3rRITA10 μMII | 1985 | 374 |
| UKF-NB-3rRITA10 μMIII | 2465 | 337 |
| UKF-NB-3rRITA10 μMIV | 3606 | 817 |
| UKF-NB-3rNutlin10 μMII | 2528 | 75 |
| UKF-NB-3rNutlin10 μMV | 6575 | 2842 |
| UKF-NB-3rNutlin10 μMVI | 4831 | 1148 |
| UKF-NB-3rNutlin10 μMVIII | 5830 | 2004 |